Iron-sulfur Clusters And Proteins: Molecular Biology And Applications

Iron-sulfur clusters are essential protein cofactors whose deficiency and defects lead to severe diseases and dysfunction of multiple cellular functions ranging from energy conversion to redox signaling. Iron-sulfur proteins have been discovered in many biological processes including DNA replication and repair, RNA modification, protein synthesis, energy metabolism, and signal transduction, so understanding these complexes is important for further studies of a rapidly expanding group of met...