Liver Stem Cells: Methods and Protocols

Increasing evidence suggests that liver stem cells have the capacity to differentiate into parenchymal hepaytes or into bile ductular cells. These stem cells may be activated to proliferate after severe liver injury or exposure to hepaarcinogens. Stem cell replacement strategies are being investigated as an alternative approach to liver repair and regeneration. Additionally, stem cell transplantation has been shown to significantly improve liver function and increase survival in experimenta...