Molecular Biology of Chromosome Function

Chromosomes have structure, determined by the interactions of proteins with DNA, and chromosomes have functions, in particular, replication of DNA and transcription of messenger RNA. Chromosome structure and function are not separate topics, since chromosome organization pro­ foundly influences the activity of the genome in replication and transcrip­ tion. This is especially clear for higher cells, including human cells, in which chromatin fibers are created by the binding of histone protei...