Nucleic Acid Crystallography: Methods and Protocols

This volume includes comprehensive and up—to—date coverage of all nucleic—acid—specific steps used in X—ray crystallography, from macromolecule production to structure determination. Chapters dedicated to RNA preparation and crystallogenesis will be of interest to beginners, while chapters focused on data collection, phasing and refinement will be particularly useful to researchers with a higher level of expertise. Several functional case studies are also presented in the last part of the b...