Opal and Oestre

In the far future, a newly out trans technowitch named Opal finds a phial of estradiol in a dusty old drawer while scavenging for relics.

After meeting the Pagan goddess Oestre who's the namesake for this wonderful elixir, she and her robot cat Remee set out on a quest to synthesize more, share it with other trans magech girls, and find the community she's always wanted.