Poly(ADP-Ribose) Polymerase: Methods and Protocols

This book presents multiple new and classical methods for studying the vital poly—ADP—ribose (pADPr) pathway. Beginning with techniques for the detection and quantification of the product of poly(ADP—ribose) polymerase (PARP) enzymatic activity and detection of variation in pADPr production during the cell cycle, the volume continues with sections on the identification of pADPr protein acceptors, methods focusing on studying molecular mechanisms of PARP functions in eukaryotic cells, partic...