Spatial Genome Organization: Methods and Protocols

This detailed volume explores a variety of cutting—edge techniques used to interrogate spatial genome organization. Beginning with a section covering the vital chromosome conformation capture (3C) technique, this collection continues with chapters on targeted Hi—C approaches, sequencing—based approaches to assess nuclear environment, as well as single—cell technologies to better characterize the heterogeneity and dynamics of nuclear architectures and approaches to visualize them by microsco...